Most Ethiopians live in the country's highlands, and have long enjoyed natural protection against mosquitoes carrying the malaria-causing parasites Plasmodium falciparum and P. vivax.
But the buffered area has been shrinking since 1981, scientists reported in the journal Environmental Research Letters. About six million people live in the newly-vulnerable regions.
Air temperatures below 18 degrees Celsius (64.4 degrees Fahrenheit) prevent development of P. falciparum. The survival threshold for P. vivax is 15 C, according to the research team.
Low temperatures also impede the spread of mosquitos that host the parasites.
Since temperatures decrease with altitude, much of the Ethiopian highlands -- 1,500 to 2,500 metres (4,921 to 8,202 feet) above sea level -- were beyond the reach of malaria transmission.
To date, it was not known whether the mercury had risen in the East African highlands, or whether global warming contributed to a recent upsurge in malaria in the region.
To find out, a team from the University of Maine and Columbia University in New York compiled a national temperature dataset for Ethiopia covering the period 1981-2014.
They discovered that temperatures rose at least 0.22 C (0.4 F) per decade.
The team then used the new climate data to pinpoint the highest elevation where the average minimum temperature never exceeds the 18 C or 15 C malaria threshold.
"The elevation at which the temperature thresholds are met has risen by more than 100 metres (328 feet) since 1981," the study's lead author Bradfield Lyon of the University of Maine, said in a statement.
Taking into account natural variability in the regional climate and impacts of the seasonal El Nino weather phenomenon, the observed rise was "consistent" with global warming caused by mankind's burning of fossil fuels, the authors found.
"Of particular concern is that the... changes are occurring in the densely populated highlands, where higher elevation has historically served as a buffer against malaria transmission," they wrote.
According to the World Health Organization, there were 212 million cases of malaria worldwide in 2015, and 429,000 deaths.
Ninety percent of malaria cases and deaths occur in Africa. Children under five are most at risk.
(This story has not been edited by NDTV staff and is auto-generated from a syndicated feed.)